B2B contact database plus sales engagement and AI prospecting platform.

Reply.io
AI Sales, Outreach & Lead GenReply.io is a sales engagement platform with sequences across email, LinkedIn, calls, SMS and WhatsApp, an embedded B2B contact database, and deliverability tools. Its Jason AI SDR agent can prospect, personalize, follow up and handle replies. It is used by SDR teams and agencies that want outreach and AI automation in one subscription.
Reply.io pricing
Free trial; paid from ~$49-59/user/mo annual (Email Volume); AI SDR from $500/mo
Last checked September 2026 · Confirm on reply.io
What Reply.io does
- Multichannel sequences: email, LinkedIn, calls, SMS and WhatsApp
- Reply Data B2B database with 1B+ contacts
- Jason AI SDR for prospecting, follow-ups and replies
- Email warm-up for connected mailboxes
- Built-in calling from sequences
- Two-way sync with Salesforce, HubSpot and Pipedrive
Pros
- Covers many channels in one sequence
- Large contact database built in
- AI SDR option for teams wanting more automation
- Deep two-way CRM integrations
Cons
- Per-user pricing adds up for larger teams
- AI SDR plans are sold separately and cost much more
- Interface has more settings to learn than simple senders
- No free plan, only a trial
Who Reply.io is for
Look elsewhere if: Solo founders sending only cold email may get a simpler, cheaper setup from Instantly or Smartlead.
Enterprise readiness
Hosted on Microsoft Azure with Key Vault encryption; publishes a DPA and states SOC 2 Type I compliance.
- Business / enterprise plan
- Yes
- SSO (SAML / OIDC)
- —
- SCIM user provisioning
- —
- SOC 2
- Type I
- ISO 27001
- —
- HIPAA (BAA available)
- —
- GDPR DPA
- Yes
- Data residency options
- —
- No training on your data
- —
- Audit logs
- —
- Admin controls
- —
- Deployment
- Cloud
From the vendor's own security documentation. "—" = not confirmed. Verify during your security review. Compare all tools.
| Sales & Outreach feature checklist | |
|---|---|
| B2B contact database | 1B+ contacts |
| Email sequences | Yes |
| Email warm-up | Yes |
| Unlimited sending accounts | AI SDR plans |
| LinkedIn steps | Yes |
| Built-in CRM | — |
| AI personalization | Yes |
| Dialer / calling | Yes |
| Email verification | Yes |
Reply.io compared
- Reply.io vs Apollo.io
- Reply.io vs Instantly.ai
- Reply.io vs HubSpot
- Reply.io vs lemlist
- Reply.io vs Smartlead
- Reply.io vs Hunter.io
- Reply.io vs Seamless.AI
- Reply.io vs Clay
Buying guides
Best Reply.io alternatives
Cold email outreach platform with unlimited sending accounts, warmup and B2B lead database.
CRM platform for marketing, sales and service with Breeze AI agents and copilot built in.
Multichannel cold outreach (email, LinkedIn, calls) with built-in lead database and AI agent.
Cold email automation with unlimited mailboxes, AI warmup and unified inbox.
Email finder, verifier and cold outreach tool with AI writing assistant.